The volume of VOXZOGO® to be administered is based on the patient’s actual body weight and the concentration of reconstituted VOXZOGO®.1 Use the VOXZOGO® Dosing Calculator to help you determine the appropriate dose for your patient.
Recommended vial strength for reconstitution should show mg on the label.
Vial should have a white, magenta, or grey coloured cap.
After reconstitution, mL should be injected.
| Body Weight | Vial Strength for Reconstitution* | Injection Volume |
|---|---|---|
| 3 kg | 0.4 mg | 0.12 mL |
| 4 kg | 0.15 mL | |
| 5 kg | 0.20 mL | |
| 6-7 kg | 0.25 mL | |
| 8-11 kg | 0.30 mL | |
| 12-16 kg | 0.56 mg | 0.35 mL |
| 17-21 kg | 0.40 mL | |
| 22-32 kg | 0.50 mL | |
| 33-43 kg | 1.2 mg | 0.25 mL |
| 44-59 kg | 0.30 mL | |
| 60-89 kg | 0.35 mL | |
| ≥ 90 kg | 0.40 mL |
* The concentration of vosoritide in reconstituted 0.4 mg vial and 0.56 mg vial is 0.8 mg/mL.
* The concentration of vosoritide in reconstituted 1.2 mg vial is 2 mg/mL.
By using this resource, you agree to the following:
This Dosing Calculator is being provided as is and is intended for use only by qualified healthcare providers. All calculations should be confirmed before use. BioMarin Pharmaceutical Inc. makes no claims as to the accuracy of the information contained herein. This calculator does not replace the need for independent clinical judgment and should be independently confirmed. The information being provided is not a substitute for clinical judgment. Neither BioMarin Pharmaceutical Inc., nor any other party involved in the preparation or publication of this site, shall be liable to you or others for any decisions made or action taken by you or others in reliance on this information.
Please also refer to the VOXZOGO® Instructions for Use.